Two targeted treatments. More options for adults with GENERALIZED MYASTHENIA GRAVIS (gMG)
gMG is a rare, chronic, autoimmune disorder that can weaken muscles throughout the entire body
With gMG, the body’s immune system mistakenly attacks and disrupts the connection between the nerves and the muscles. This causes most people with gMG to experience muscle weakness and muscle fatigue. These symptoms can range from mild to severe and can affect any part of your body.
“Life with gMG is not a journey; it is an odyssey. You never know what is going to come up and throw off your goals.”
Why targeted treatment for gMG?
While some treatments can help ease symptoms, they may not target any underlying mechanisms of gMG. As a result, there has been an urgent need for more treatment options that target the causes of gMG symptoms to help those still suffering from this rare disease.
Targeted treatment for gMG is a type of therapy that affects specific parts of the immune system causing the disease. Unlike traditional treatments that focus on the broader immune system to help ease symptoms, targeted therapies aim to block or change the action of certain proteins or immune cells directly involved in the disease.
UCB offers treatments that target gMG in two different ways:
An FcRn blocker
Harmful antibodies that cause gMG may stay in your body longer because of FcRn (neonatal Fc receptor) proteins.
A C5 inhibitor
Harmful anti-acetylcholine receptor (AChR) antibodies activate part of your immune system called "complement" which works to attack your muscle cells.
“I think anytime you are affected by a physical illness, you have to take a look at it as a learning opportunity. There is a lot to be gained from it.”
Rethinking your
gMG treatment
If you’re struggling with poorly controlled gMG, share your challenges with your doctor to help them better understand your unique experience with this condition. Ask if targeted treatment may be right for you.
Find tips for a productive conversation in our Doctor Discussion Guide.
